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DrugPioneerMax Freq.DurationPreloadPostProblemsAntidoteBrainmachine Program
DMTTerrence McKennaFew5 minSyrian Rue   Visualization
LSDTimothy Leary3-4/year8 hoursVitamin C SchizophrenicsNiacimideImagination
KetamineJohn Lilly1/ week max.45 min.CholineCholineAddiction, Olney’s LesionsSugarOOBE
MDMASasha Shulgin1/month4-6 hours5HTP, Vitamin C, MelatoninMelatonin,  1 SSRIDepression, depleted serotoninSSRIs10hz
MDA (Trippier, not as euphoric as MDMA)Sasha Shulgin1/month7-9 hours5HTP, Vitamin C, CalciumMelatoninSee MDMASSRI’s10hz
2CB (Aphrodisiacal, more control than MDMA, trippier, weaker w/LSD or MDMA6 hours    Tantra
Peyote  6 hours     
Psilocybin   Syrian Rue   Schuman Resonance
MescalineAldous Huxley      Visualization
THC  3 hours  Temporary short term memory lossVasopress in 

Advice when taking illegal drugs

If you must do E, you should take absolutely Vitamin C and 5HTP beforehand and 5HTP and Melatonin afterwards. And don’t do it very often, never more than once every two weeks.
If you must do LSD, Ascorbic Acid (Vitamin C) will take the edge off, if that is what you want, and Niacinimide will stop the effects. Parents, take note.
If you must do Ketamine, take Choline beforehand to protect your kidney. And don’t do it very often, never more than once a week.

Legal Substances
Nyphaea Caerulea (Blue Lotus) is an interesting drug taken by ancient Egyptians. Mild aphrodisiac and mood enhancer. Great with coffee.
Mucuna Pruriens (Mustard Wort) is an ancient ayurvedic herb that replenishes dopamine that is consumed by cocaine use. For this reason it can allow cocaine to be sverely used to excess, thus is dangerous. Exactly the right amount has to be taken or it causes stomach cramps. Also an aphrodisiac and soporific, even while using cocaine.
Ayahuasca can be readily made with combinations of various legal plants. Wikipedia

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Alex Grey BIO St. Albert And The Lsd Revelation Revolution

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Acid Dreams – The Complete Social History of LSD The CIA, the Sixties, and Beyond – Martin A. Lee, Bruce Shlain – 1994

Albert Hofmann
LSD – My Problem Child – 1979
Plants of the Gods – 1979
The Road To Eleusis – Unveiling the Secret of the Mysteries– with Gordon Wasson – 1976

Altered State The Story of Ecstasy Culture and Acid House – Matthew Collin – 1997

Ayahuasca Visions – Pablo Amaringo – 1999

Daniel Pinchbeck
Breaking Open The Head – 2002
The Return of Quetzalcoatl – 2012
Toward – 2012 Perspectives on the Next Age – 2008

DMT the Spirit Molecule – Rick Strassman – 2000

Generation Ecstasy – Into the World of Techno and Rave Culture – Simon Reynolds – 1998
Global Tribe Technology, Spirituality and Psytrance – Graham St. John – 2012 (Click link to download PDF)

Journeys into the Bright World – Marcia Moore and Howard Sunny Alltounian – 1978
Ketamine Dreams – Karl Jansen – 2000
LSD Doorway to the Numinous – Stanislav Grof – 1975
LSD: Hollywood’s Status Symbol
Manifesting Minds: A Review of Psychedelics in Science, Medicine, Sex, and Spirituality – Rick Doblin, Brad Burge, Albert Hoffman, Ram Dass, Sasha Shulgin – 2014
Microdosing Psychedelics – Paul Austin – 2018

Peter Stafford
LSD The Problem-Solving Psychedelic – 1967
Psychedelics Encyclopedia – 1993

Psychedelic Information Theory – Shamanism In The Age Of Reason – James Kent – 2010

Ralph Metzner
Ecology of Consciousness The Alchemy of Personal, Collective, and Planetary Transformation – Ralph Metzner – 2017
Sacred Vine of Spirits, Ayahuasca – Ralph Metzner – 1999

Ram Dass
Be Here Now – 2010
Grist for the Mill – Awakening to Oneness 2014
Miracle of Love Stories about Neem Karoli Baba – 1979
Paths to God Living the Bhagavad Gita 2004

Sacred Mirrors – Alex Grey – 1990

Sasha & Ann Shulgin
PIKHAL – A Chemical Love Story – 1990
TiHKAL – The Continuation – 1997
Secret Drugs of Buddhism – Ann Shulgin & Mike Crowley – 2017

Seasoned Exodus – The Exile Mosaic of Psyculture – Graham St. John – 2012

Sex Drugs Einstein Elves Sushi Psychedelics Parallel Universes and the Quest for Transcendence – Clifford Pickover – 2005
Shroom- A Cultural History Of The Magic Mushroom – Andy Letcher – 2006
Trip – Psychedelics, Alienation, and Change – Tao Lin – 2018
Teachings Of Don Juan A Yaqui Way Of Knowledge – Carlos Castaneda – 1968

Terence McKenna
Food of the Gods – 1992
The Archaic Revival – 1991
The Invisible Landscape – 1975
True Hallucinations- Being an Account of the Author’s Extraordinary Adventures in the Devil’s Paradise – 1994

The Divine Spark – Hancock, Graham – 2015
The Doors Of Perception – Aldous Huxley – 1954
The Electric Kool-Aid Acid Test – Tom Wolfe – 1968
The Harvard Psychedelic Club How Timothy Leary, Ram Dass, Huston Smith, and Andrew Weil Killed the Fifties and Ushered in a New Age for America – Don Latin – 2010
The Joyous Cosmology – Adventures in the Chemistry of Consciousness – Alan Watts – 1962
The Presence of the Past: Morphic Resonance and the Habits of Nature – Rupert Sheldrake – 1988
The Scientist – A Metaphysical Autobiography – John C. Lilly – 1978
The Varieties Of Religious Experience – William James – 1902

Timothy Leary
Chaos & Cyber Culture – 1994
Flashbacks – 1983

Updated 1 year ago

Shamanism

The discovery of the Western Hemisphere has been the most momentous occurrence to mankind in the last millennia. As the Europeans, upon discovering the New World, have only had 500 years to take in all the new plants to their full society-wide potentials, I propose harnessing both the past – traditional shamanic practices developed over thousands of years – with the new cutting edge of Western science, assembling a truly holistic, multidisciplinary curative arsenal. These items may befit a shaman’s pouch, or even an event vendor, within reason.

First off, let’s briefly go over what shamans have traditionally worn. As per Encyclopedia Brittanica, “a shaman wears regalia, some part of which usually imitates an animal—most often a deer, a bird, or a bear. It may include a headdress made of antlers or a band into which feathers of birds have been pierced. The footwear is also symbolic—iron deer hooves, birds’ claws, or bears’ paws. The clothing of the shamans among the Tofalar (Karagasy), Soyet, and Darhat are decorated with representations of human bones—ribs, arm, and finger bones. The shamans of the Goldi-Ude tribe perform the ceremony in a singular shirt and in a front and back apron on which there are representations of snakes, lizards, frogs, and other animals.”

Mongol shaman

What’s in Your Wallet?

Now, let’s shift beyond mere appearances and go into the shamanic core: the bag. To keep things simple, let’s use Native Americans as a focal point. A Native American medicine bag or medicine bundle is a container for items believed to protect or give spiritual powers to its owner. Varying in size, it could be small enough to wear around the neck, or it could be a large bag with a long strap called a “bandolier.” The size of the bag is determined by how many items need to be carried.

In historical times, medicine men and shamans generally carried a large medicine bundle that could hold numerous items such as seeds, herbs, pine cones, grass, animal teeth or claws, horsehair, rocks, tobacco, beads, arrowheads, bones, or anything else of relatively small size that possessed spiritual value to the bundle’s owner. Warriors also carried bundles that included important items, such as rattles, animal furs, special stones, or anything that meant something to the owner.

Because the medicine bag is considered a very precious possession representing a person’s spiritual life, it and its contents are generally regarded as holy by the tribal community. Its contents are meant to be kept secret by the owner. The bundle should never touch the ground, which is why the bundles are to be securely wrapped. Prayers and rituals usually accompany the manufacture and opening of medicine bundles.

Medicine bundles can also be maintained for an entire tribe. This bundle would be much larger and contain special objects that can only be handled by certain tribe members and are only opened on special occasions. All bags and bundles can possess powers for protection, good luck, good hunting, or healing. Medicine bundles are sometimes buried with the owner or handed down from one generation to the next.

In traditional Native American medicine, the pouch or bundle is usually made out of leather and stitched with sinew or rawhide lace to be worn or hung. They can also be made using cloth. The bags might be very plain or richly decorated. Of the latter, they might be painted, beaded, or quilled with tribal designs, medicine wheels, totems, and more. Embellishments might include feathers, beads, metal, fringe, etc.

In many cultures, some of the items carried in the bag would often be procured through a vision quest, a right of passage that includes personal sacrifice such as fasting and prayer over several days in an isolated location. The purpose is to contact natural spiritual forces that will guide the individual in reaching their potential and increase their understanding of themselves, their community, and the world. During the vision quest, a guardian spirit will generally come to the individual in a dream or a vision, which is afterward interpreted with the help of a Shaman. Some items within the individual’s medicine bag would represent their guardian spirit.

Though many people associate medicine bags with the native tribes of North America, they have been used by numerous cultures throughout the world.

The use of medicine bags dates back at least 5,000 years, as evidenced by ancient “iceman” remains found high in the Swiss Alps in 1991. Among his possessions was a medicine pouch. Other historians believe the use of these bags dates back even further — as far as 10,000 years — based on murals found in an ancient city excavated in Turkey.

from Legendsofamerica.com

This page will be continuously updated. Please send me your suggestions!

Shaman’s Pouch

ItemCategoryAvailabilityUse
2C-B
(Also see page on this site)
Empathogen/PsychedelicScheduledSensuous nexus of MDMA and psilocybin
2C-IPsychedelicOne of the classic “research chemicals”
3D Chromadepth GlassesAccessoriesUse with art books such as Alex Grey’s Sacred Mirrors
5-MeO-DiPT (Foxy methoxy)PsychedelicAudial hallucinations. Don’t be like Tony and take too much.
5-HTPNootropica serotonin precursor in the brain. It is a naturally occurring byproduct of the amino acid tryptophan. Serotonin is a neurotransmitter that helps communication between neurons.

5-HTP as a nootropic easily crosses the blood-brain barrier. And once it converts to serotonin can help improve mood, control behavior and appetite, and help you sleep.

Research shows 5-HTP can help in impulse control, and balance out moods resulting in less anxiety.[iv] And even reduce panic attacks.
5-MeO-DMT (Toad venom)Psychedelic“The big bang”
AbsintheDeliriantFashionable 19th century concoction, popular with artists such as Degas and Van Gogh, but really not that notable an effect
AdderallStimulantScheduledMiddle class meth
Afrin/Nasal SprayMedicinalDo not overuse
Alpha-Lipoic Acid (ALA)NootropicThis antioxidant is necessary for cellular energy production. And helps eliminate the free radicals created when nutrients convert to cellular energy.
Acetyl L-Carnitine (ALCAR)NootropicTargets your brain metabolism, boosts mitochondria energy, and acts as a neuroprotectant; boosts memory, mental alertness, fluid thought, and is a strong antioxidant.
Alcohol (190-Proof Organic Grape)AccessoriesIdeal base for liquid LSD
Alcohol WipesMedicinal
Alpha-GPCNootropicEasily crosses the blood-brain barrier. It boosts acetylcholine levels in your brain contributing to improved memory, cognition, learning and focus. And protects against age-related memory loss.
AMTPsychedelicVery long lasting trip
Amyl NitratePsychedelicPoppers
AniracetamNootropicAn N-side chain derivative of piracetam. It is thought to be 5 to 8-times more potent than piracetam. Aniracetam is fat-soluble and has a shorter half-life compared to other racetams.
A potent nootropic, Aniracetam reduces anxiety and depression with no sedative effects. It seems to do this by activating the D2 and D3 Dopamine receptors in the brain. Aniracetam helps improve memory, learning, cognition, along with heightened reflexes and perception.
The fastest harshest smart drug. Use it to fire slacking workers.
Artichoke Extract (Luteolin)NootropicImproved cognition, memory, wakefulness, and protecting neurotransmitters in your brain.


Artichoke Extract is even more powerful when combined with Forskolin to significantly boost cAMP (brain signaling) levels.
AshwagandhaNootropicAshwagandha has been used in Ayurvedic medicine for several thousand years. In Sanskrit it literally means “the smell of a horse” which implies this herb provides the vigor and strength of a stallion.

As a nootropic, Ashwagandha helps relieve stress, fatigue, restore energy and boosts concentration. As an adaptogen, it helps your entire body by normalizing blood sugar, boosts insulin sensitivity, works as an antioxidant, promotes breast, lung and colon health, and protects against inflammation.
AspirinMedicinalThe most important item to have in your bag!
AstaxanthinNootropicOne of the few antioxidants that can cross the blood-brain barrier and blood-retinal barrier, benefiting both your brain and vision.

As a nootropic, Astaxanthin is a potent antioxidant and anti-inflammatory providing protection from Alzheimer’s, Parkinson’s disease, and other neurodegenerative disease.

Astaxanthin protects your cells from the destructive effects caused by free radicals and protects cognitive function by increasing cerebral blood flow for better memory and overall cognitive performance.
Ayahuasca Visions of Pablo AmaringoAccessoriesIdeal for using with the 3D glasses
Ayahuma barkAyahuasca admixture
Bacopa MonnieriNootropicAdaptogen that helps prevent the chemical and physical effects of stress. Instead of just suppressing them like many modern antidepressants.

Bacopa Monnieri is used to reduce anxiety, depression, and stress. It’ll boost memory, concentration and reaction time. And is used for neuroprotection, and to balance neurotransmitters.

The compound Bacoside A easily crosses the blood-brain barrier. And binds to receptor sites to increase cognition and memory. It has been shown effective in treating ADHD.
BaggiesAccessories
Band AidsMedicinal
BandagesMedicinal
Banisteriopsis caapi (Ayahuasca vine)Ayahuasca admixtureMAOI. The best.
The older and thicker, the better
Vicki Holding Banis
Bath SaltDeliriant
BellAccessories
BelladonnaMedicinal
BenadrylMedicinal
BerberineNootropicBerberine is one of the very few nootropic supplements known to activate AMPK (another is Resveratrol).

Activating AMPK is especially relevant if you’re diabetic, pre-diabetic, or over-weight. All conditions that negatively affect cognition. Research and clinical experience has shown Berberine to be as effective in controlling diabetes as the prescription drug metformin.

Berberine is one of the most powerful (literally) nootropic supplements on our List of Nootropics. Not only can Berberine help control diabetes, but you may find sugar cravings disappear. No crashes late afternoon. Energy levels and stamina increase.

Adding Berberine to your nootropic stack can help improve cholesterol levels, lower blood pressure, improve your mood, protect your brain from damage, and help memory.
Betel NutStimulantDo not use if you like white teeth
Black Seed OilNootropicIts main active compound thymoquinone (TQ) has been shown to benefit cognitive and mental illness, cardiovascular disorders, cancer, diabetes, inflammation, and infertility.

The Prophet Mohammed was said to have described the curative powers of Black Seed Oil as, “it has a remedy for every illness except death”.

As a nootropic, Black Seed Oil acts as a powerful acetylcholinesterase inhibitor which boosts acetylcholine. Supporting improved alertness, learning and memory.

Black Seed reduces tumor necrosis factor-α (TNf-α) which helps fight inflammation. And it boosts brain-derived neurotrophic factor (BDNF) which supports better learning and memory, and brain cell repair.

Studies and practical experience by neurohackers show Black Seed Oil effective for reducing anxiety, reducing seizure frequency, and helpful with opiate withdrawal.
Black teaFood
Blue LotusNarcoticUsed by ancient Egyptians
BobinsanaAyahuasca admixture
Brain MachinesNeurotech
Breath MintAccessoriesIdeal to hold liquid LSD
CacaoNootropicCocao powder is at the base of all things made of chocolate.

Cacao as a nootropic offers a hosts of cognitive benefits. It stimulates the release of phenylethylamine (PEA) which boosts focus and awareness. And anandamide (the bliss molecule) which increases happiness levels. Cacao is a source of tryptophan which is the precursor to serotonin. And theobromine which boosts blood flow, is a stimulant, and may account for chocolate’s aphrodisiac qualities.

Studies show that consumption of a flavanol-rich cocao drink increases blood flow for up to 2 hours in certain regions of the brain. Improving cognition, memory, and preventing neurodegeneration.

And cacao beans are one of the richest sources of antioxidants available. Reducing free radicals that would normally cause oxidative damage in your brain and body.

But cacao and chocolate are NOT the same thing. How cacao is processed makes all the difference in retaining its nootropic benefits.
CaffeineNootropicCaffeine is the most widely used psychoactive drug in the world. As a nootropic, caffeine helps improve reaction time, alertness, memory and mood.

Caffeine is an adenosine antagonist which influences acetylcholine, epinephrine (adrenaline), serotonin and boosts the use of dopamine. Providing the stimulant effect experienced when consuming caffeine.

Caffeine provides a protective effect by boosting gene expression of brain-derived neurotrophic factor (BDNF). Studies show chronic caffeine consumption may protect against developing neurodegenerative diseases like Alzheimer’s and Parkinson’s.

Caffeine improves mood within an hour of consumption. Because it increases the density of GABA receptors, potentiates dopamine, and causes some serotonin receptors to be more responsive.
Calamine LotionMedicinal
CandleAccessories
CannabisPsychedelic
Capirona barkAyahuasca admixture
L- CarnosineNootropicAn amino acid or dipeptide found in your kidneys, liver, muscles and brain. The two amino acids are beta-alanine and L-histidine.

L-Carnosine works in the body as an antioxidant scavenging for free radicals. The concentration in muscles correlates with life span so it’s considered a powerful anti-aging supplement.

L-Carnosine is involved in neurotransmission, binds to and helps remove AGEs (Advance Glycosylation End-products), helps in the treatment of Alzheimer’s, and assists in removing heavy metal toxins.

While you may not see profound and immediate nootropic benefits using L-Carnosine, hundreds of studies prove its benefits for long-term health and anti-aging.
Cat’s ClawNootropicPotent anti-inflammatory and antioxidant effects that support DNA repair, immune function and normal cell division.

For cognitive health, Cat’s Claw (Uncaria tomentosa) has been used to prevent inflammation, promote cerebral circulation, fight amyloid plaques in Alzheimer’s and possibly even boost acetylcholine (ACh).
CBD OilNootropicCBD does not have the same psychotomimetic (mind-altering) effects as the main plant compound THC (Δ9-tetrahydrocannabinol). In fact, CBD is able to counter the mind-altering effects caused by THC.

CBD Oil is used as a nootropic for its antianxiety and antidepressant effects, helps alleviate pain, reduces oxidative stress and inflammation and is anti-tumor.

Research into CBD has rapidly gained traction in the last few years. And shows potential in the treatment of depression, neuroinflammation, epilepsy, oxidative stress, vomiting and nausea, anxiety, schizophrenia and other neurodegenerative problems.

Note that CBD Oil and hemp oil are not the same and should not be confused. You will not experience the same nootropic benefits with hemp oil as you will with CBD Oil.
CDP-CholineNootropic CDP-choline is a highly bioavailable source of choline that easily crosses the blood-brain barrier.

CDP-Choline is metabolized in the body to form choline and cytidine.[i] In the body choline aids in the synthesis of acetylcholine in the body. Acetylcholine is a neurotransmitter associated with memory and learning.

The cytidine in CDP-Choline converts to uridine in the body. This nucleotide is important to neural membrane synthesis which helps cognition or thinking.
CedarEssential OilSedative, pain, acne, pesticode
CentrophenoxineNootropicA water-soluble derivative of DMAE. It is a precursor to acetylcholine in the brain. And once metabolized by your liver, it readily crosses the blood-brain barrier.

DMAE is a natural chemical found in your body. It works on boosting cognition and mood. Centrophenoxine seems to be more effective than DMAE when used as a supplement.

Marketed in Europe as “Lucidril”, its prescribed to treat Alzheimer’s and ADHD.
CerebrolysinNootropicPig’s brain. Big in Russia.
CES (Cranial Electrical Stimulation)Neurotech
Chacruna LeavesAyahuasca admixture
ChapstickMedicinal
ChlorineAroma
Choline BitartratelineNootropicCholine is an essential nutrient needed by your body. And cannot make it on its own. Choline is arguably the most basic of nootropics.

It is a water soluble nutrient required for the health of cell membranes. Choline is also the precursor to the neurotransmitter acetylcholine.

Food sources of choline are egg yolks, liver, milk and other dairy products, certain grains like quinoa and amaranth, bacon, edamame and cruciferous vegetables.

Brain health is compromised by too little choline. And with our modern diet it is nearly impossible to get enough choline without supplementation.

Choline as a nootropic is used as an acetylcholine precursor. In other words, it’s the step before producing acetylcholine in your brain.

Common signs of choline deficiency can include; headaches, fatigue, memory problems, and muscle pain.
Choline BitartrateNootropicA “choline salt”, and one of the least costly sources of choline as a nootropic supplement. Its a weaker source of choline than Alpha GPC and CDP-Choline. Meaning you need to use more to achieve similar nootropic effects.
Choline CitrateNootropicCholine Citrate is effective as a nootropic when use in large enough doses. It assists in boosting memory and recall, cognitive abilities, helps concentration and even used to treat brain diseases such as Alzheimer’s.

Athletes like choline citrate for its ability to assist in cellular and muscle health and repair.
Chromium PicolinateDietary Supplement
Chullachaki barkAyahuasca admixture
Chumpi stonesAccessories
Citronella EmitterInsect Repellent
ClaritinMedicinal
ClovesEssential OilBlood sugar, antiobacterial
Coca leavesStimulant
CocaineStimulantScheduled
Coconut & MCT OilNootropicCoconut oil is 90% saturated fat. Nearly 60% of the fats are medium-chain fatty acids. Including caprylic acid C-8 (8%), capric acid, C-10 (7%), and lauric acid C-12 (49%).

Medium-chain fatty acids are also known as medium-chain triglycerides (MCTs). MCTs are produced by hydrolyzing coconut oil and esterifying the fatty acids shorter than lauric acid (C-12) with glycerol.

Both coconut and MCT oil provide some powerful nootropic properties. The MCTs in coconut oil bypass your normal digestive system and go directly to your liver where they are converted to ketones.

Ketones are carried throughout your body including your brain for use in the citric acid cycle to produce Adenosine Triphosphate (ATP). ATP fuels your mitochondria which improves alertness, cognition, memory and mood.

MCTs help increase antioxidant levels in your brain. And increase serotonin which provides an anti-stress effect.
CodeineOpioidScheduled
Coffee Grinder, manualAccessoriesVery helpful in preparing various teas
Cold pack (instant)Medicinal
ColuracetamNootropicEnhances concentration and cognition, boosts memory, mood and focus, and treats anxiety disorders. It also seems to have a stimulant effect which improves motivation. Users also report richer and fuller sound and colors.
CombAccessories
CompassAccessories
Compression BandagesMedicinal
CondomAccessories
CoQ10 & UbiquinolNootropicCoQ10 is essential to mitochondria for producing Adenosine Triphosphate (ATP). The Ubiquinol version of CoQ10 is highly bioavailable and easily crosses the blood-brain barrier. As a nootropic, CoQ10 not only helps produce ATP in brain cells, but protects against free radical damage as well.[ii]

CoQ10 improves athletic performance, works as an antioxidant, and battles fatigue and depression.
Corn pollenAccessories
CrackStimulantScheduled
CreatineNootropicGood for muscles. Creatine is made in the liver, and acts as fuel cells for your cells. Including brain cells. It provides energy on demand. You could say creatine is the ultimate nootropic.

Creatine is a popular supplement for athletes because it boosts physical performance by going directly to the muscles needing fuel. Vegetarians and vegans typically have lower levels of creatine in the body than meat eaters.

Creatine is also favored by nootropic users because of the fuel demanded by brain cells when using racetams. After crossing the blood-brain barrier, creatine binds to phosphate. Creatine phosphate in turn fuels energy consumption by the brain.

So creatine is good for muscle fuel, and mental performance. It helps boost memory, reducing brain fatigue, improve mood, is anti-aging and a neuroprotectant.
CrystalAccessories
Crystal ballAccessories
DaturaDeliriantSuper glue wolves heads popping out of nowhere. Older shamans would give this to younger shamans to teach them a lesson. Dose is wildly variable. Withces put it on broomsticks and inserted into their vaginas to be able to “fly”
Deck of cards/TarotAccessories
DeodorantAccessories
DHA (Omega 3)NootropicYour brain is 60% fat. So it would be safe to say that to maintain and excel mentally, our brain needs a good supply of healthy fats.

The two most studied omega-3 fatty acids are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). DHA makes up a large portion of brain gray matter. Brain fat forms cell membranes. And plays a vital role in how our cells function. Neurons are also rich in omega-3 fatty acids. DHA is a main component of brain synapses. (A synapse is the part of a brain cell that causes a neuron to pass an electrical signal to another neuron).

Low levels of omega-3 fatty acids result in ADD, anxiety, depression, obesity, suicide, and an increased risk of Alzheimer’s disease and dementia.

Diets rich in omega-3’s help balance emotions and boost mood because DHA is a main component of the brain’s synapses.

Eating fish helps cognitive performance because fish, krill, and other marine life are high in Omega-3’s. Other foods high in Omega-3 fatty acids include: anchovies, broccoli, Brussel sprouts, cabbage, cauliflower, flaxseed, soybeans, walnuts, spinach, and tofu.
DHEANootropicDHEA (Dehydroepiandrosterone) is a hormone produce by your adrenal glands, brain, and testes in men. DHEA levels decline with age right along with testosterone. The result is deceased motivation, cognition, depression, fatigue, and loss of libido.

DHEA as a nootropic has a noticeable effect on increasing motivation, and a general sense of well-being.

Remember that DHEA is a steroid hormone, and does increase estrogen. In men prolonged elevated estrogen levels has negative effects like abdominal fat, and male breasts.
DiceAccessories
DiPT (Diisopropyltryptamine)Psychedelic
DiprophyltryptaminePsychedelicUsed by the Temple of the True Inner Light
DMAENootropicDMAE prevents choline metabolism by cells and boosting choline levels in the brain as a result.

DMAE as a nootropic helps increase alertness, boosts mood and memory. Studies show that DMAE supplementation may help improve mood.[iii]

Use of DMAE as a nootropic has mixed reviews in the neurohacking community. Some report benefits to increased energy. And others say it causes hyperactivity, loss of focus and motivation, and depression. Most of the negative effects of DMAE come from higher and prolonged dosing.
DMSOMedicinalPropels chemicals on the skin surface underneath; used to treat herpes with food grade H2O2
DMTPsychedelicScheduled
DramamineDeliriantIn loving memory of Zoe7
Drinking cup/ChaliceAccessories
DrumAccessories
Duct tapeAccessories
DXMDissociativeScheduledPoor man’s Ketamine
Eagle featherAccessories
EarplugsAccessories
Emergency BlanketAccessories
EphedrineStimulant
ErgotamineIngredient
Essential Oil DiffuserAccessories
EtherDissociative
EucalyptusEssential Oil
FentanylOpioidScheduledPut this here as somewhat of a troll, all in the pursuit of completionism
Fingernail ClippersAccessories
FisetinNootropicA flavanol found in fruits and vegetables such as strawberries, apples, persimmons, grapes, onions, and cucumbers.

fisetin is a potent senolytic nootropicFisetin is one of the most potent anti-aging compounds found in nature. It has been shown to increase long-term potentiation needed for encoding long-term memory.

Studies show Fisetin protects neurons from damage due to oxidative stress. It boosts Glutathione which is your main antioxidant protecting against inflammation. And it suppresses gene expression of pro-inflammatory cytokines which provides potent anti-inflammatory benefits for your brain.

Neurohackers who supplement with Fisetin report better focus, memory, and mood. Some say they are more alert even when they haven’t had sufficient sleep.
Flare Accessories
Floro/DayGlo PaintAccessories
Fog MachineAccessories
Forskolin (Coleus root)NootropicA plant native to south Asia. And has a limited nootropic track record. It first became popular when included in the open source stack CILTEP.

Forskolin combined with artichoke extract boosts cAMP levels in the brain. Leading to improved memory, and ability to reason.
Four ThievesEssential OilThis specific vinegar composition is said to have been used during black death epidemic of the medieval period, to prevent the catching of the plague.[3] Similar herbal vinegars have been used as medicine since the time of Hippocrates.
GABAGABANootropicAn amino acid and neurotransmitter produced by glutamate in your brain. GABA in the brain is considered an inhibitory neurotransmitter which means is prevents other neurotransmitters from being released. Resulting in an anti-anxiety and calming effect.

There is considerable debate on whether GABA as a supplement can cross the blood-brain barrier. But many find it effective for relieving anxiety, stress and for sleep.
Ganzfeld Effect (Ping Pong balls cut into eye socket shapes)Neurotech
Garlic cloveFood
GarlicMedicinal
GauzeMedicinal
GHBDepressantScheduled
Gimsacha (larch wand)Accessories
GingerMedicinal
Ginkgo BilobaNootropicparticularly effective in elderly memory loss, slow thinking and reasoning, and tinnitus. One study shows significant improvement in Parkinson’s and Alzheimer patients.[v]

nootropoics-GINKGO-Biloba-treeMost noticeable in adults suffering cognitive decline, Ginkgo Biloba seems to improve short term memory and recall. It’s also effective in reducing stress and anxiety, and boosting mood.
GinsengNootropicImprove symptoms of anxiety, and boost attention, concentration, and memory. Nootropic users above 40 find the most benefit in Ginseng.

Panax ginseng is native to southeast Asia. Other species include American Ginseng and Siberian Ginseng. Each have unique characteristics. Panax Ginseng is preferred, and is used as a memory booster, improves mood, lower anxiety levels, and boosts stamina and endurance.
Glass pipeAcccessoriesAhem For DMT
lay cigarette ashes on screen then layer DMT powder then ashes again
GlitterAccessories
Gloves, disposable, sterileMedicinal
GlowstickAccessories
GlutathioneNootropic a tripeptide made up of cysteine, glycine, and glutamine and present in high concentrations in every cell in your body.

As an antioxidant, Glutathione’s primary role is to protect your cells from free radical damage. And plays a vital role in detoxification.

Supplementing with Glutathione may help reduce brain fog and poor cognition. It plays a role in preventing and treating neurodegenerative disease, including Alzheimer’s disease, bipolar disorder, obsessive compulsive disorder (OCD) and autism.

Neurohackers who supplement with Glutathione report increased energy levels, better memory, improved digestion, decreased inflammation, clearer thinking, improved skin tone, and stronger hair and nails.

And Glutathione helps prevent neurodegenerative disease such as Alzheimer’s disease and dementia.
GlutamineNootropicIncreases the effectiveness and activity of neurotransmitters. Helping with improve focus, energy, cognition and retention when learning.

L-Glutamine in your brain works by boosting glutamic acid and gamma-aminobutyric acid (GABA). It also helps detox toxins and free radicals from your brain.

And by increasing GABA levels, L-Glutamine can lead to reduced stress and better sleep.
GlycineNootropica conditionally essential amino acid that plays a role in the synthesis of nucleic acids, glutathione, RNA and DNA, and creatine.

Glycine activates NMDA receptors in your brain and restores serotonin levels which helps improve sleep. And the ability to fall asleep faster.

And Glycine taken in high doses has proven effective in reducing symptoms of schizophrenia.
Goji berriesFoodDon’t buy from China proper. The soil is terrible.
Gotu KolaNootropicone of the most important herbs in ancient Ayurveda medicine. Ayurveda uses it to reduce anxiety, reduce fever and treat skin conditions. It improves circulation and promotes longevity.

Unfortunately, our brains also shrink as we age. Brain growth factor seems to diminish. But clinical trials show gotu kola extract can help spur growth in brain cells.[vi]

Users report gotu kola is at least as effective – perhaps even more so – in reducing anxiety and relieving stress than Ashwagandha and Phenibut.
Grapeseed OilAccessoryIdeal carrying oil
Grinder (Cannabis)AccessoriesBuy from Joann in the link provided!
Grinder (Powder)Accessories
Guarana PowderStimulantSuper caffeine.
Heat pack (instant)Medicinal
HeroinDepressantScheduled
HGHMedicinal
Holy Basil (Tulsi)Nootropic“The Incomparable One” is the most sacred plant in the Hindu religion. And has been valued for millennia by Ayurveda, Greek, Roman, Siddha and Unani because of its benefits for mind, body and spirit.

Supplementing with Holy Basil increases levels of dopamine, is a monoamine oxidase inhibitor (MAOI), and inhibits acetylcholinesterase (AChE) which boosts acetylcholine.

Holy Basil reduces spikes in cortisol induced by chronic stress. And is particularly effective in reducing stress caused by loud noise.

Holy Basil is also a potent antioxidant. It’s a natural COX-2 inhibitor. And the compounds including eugenol, cirsilineol, cirsimaritin, isothymusin, isothymonin, apigenin, rosmarinic acid in Holy Basil have been compared to the pain-relieving activity of ibuprofen, naproxen and aspirin.

Many neurohackers use Holy Basil as an anxiolytic and find it as effective for calming anxiety as some prescription anti-anxiety meds.
HuacapuranaAyahuasca admixture
Huperzine-ANootropicA natural compound extracted from the Chinese club moss huperzia serrata. Huperzine-A is an acetylcholinesterase inhibitor which means it boosts levels of the neurotransmitter acetylcholine in your brain.

Huperzine-A helps promote memory by increasing acetylcholine levels. Users report improved memory, retention, cognition, and lucid dreaming.
Hydrogen Peroxide, food gradeMedicinal
Hypodermic NeedleAccessories
IbogaPsychedelicAddictions
IdebenoneNootropic, AntiagingIdebenone is claimed to have properties similar to CoQ10 in its antioxidant properties, and has therefore been used in anti-aging on the basis of free-radical theory.
IodineNootropicA cognitive enhancer not talked about much in the nootropic community. Iodine deficient populations are up to 13.5 IQ points less than normal populations.[vii]

Since iodine has largely been removed from table salt in some countries, many suggest an iodine deficiency epidemic. Particularly in countries like the United States.

Iodine is essential to a healthy thyroid. Remember, your thyroid is right next to your brain. Iodine deficiency during early childhood results in profound intellectual disability.

The thyroid hormones T4 and T3 are synthesized from iodine and tyrosine. These help regulate processes like growth and metabolism. Thyroid hormones target organs like the brain where they regulate gene expression. And help protect brain cells from toxins.

Ask anyone suffering from hypothyroidism about brain fog!
JerkyFood
Kananga waterAccessories
Kava KavaNootropicNative to the South Pacific. Pacific Islanders traditionally use the plant for its sedative effects.

Kava can help to reduce anxiety, improve mood, and promote an overall sense of well-being. And unlike benzodiazepines, kava does not impair cognitive function. In fact, studies show kava may boost cognitive function.[viii]

Of the 105 varieties of kava, Noble and Tudei Kava has been traditionally used in the South Pacific Islands. And has been safely consumed for hundreds of years.
Ketamine
Also see page on this site
Dissociative/PsychedelicScheduled“Literally, chemically, astral travel” (See video on link)
KratomNootropicMitragynine and 7-hydroxymitragynine (7-HMG), unique to Mitragyna speciosa, are the two alkaloids mainly responsible for the effects of Kratom. And are agonists of the μ-subtype opioid receptor (MOR). Which provides its powerful pain-relieving action.

5-HT2a (subtype of serotonin receptor) and postsynaptic α2–adrenergic receptors, as well as neuronal Ca2+ channels are also involved in the unique mechanism of action of mitragynine.

Kratom’s effect on serotonin and norepinephrine help improve mood and lower anxiety. At lower doses, Kratom is used for its stimulant effects and to combat fatigue.

At higher dosages, Kratom can have more of a sedative and anxiolytic effect. And has also been used in traditional and natural medicine as an alternative to opiate medications.
KrokodilOpioid
Double rapé kuripeAccessories
Laptop with VRAccesssories
LavenderEssential OilGreat for sleeping; repels insects
Lawyer’s Business CardAccessories
LED Flashlight (on head band)Accessories
LemonEssential Oil
Lemon BalmNootropicUsed for its anti-anxiety effects. This plant from the mint family has a lemony scent, and is native to the Mediterranean region.

Rosmarinic acid, a compound found in lemon balm, inhibits the GABA transaminase enzyme. Which in turn helps maintain adequate levels of GABA in your brain. Resulting in a calming effect.

As a nootropic, lemon balm is most commonly used for stress relief, and reduction of panic attacks. Lemon balm also helps with focus, concentration, reduces irritability and depression, and improves memory and learning retention.
LighterAccessories
Lion’s ManeNootropicAn ancient Chinese remedy for improving cognitive performance, and overall health.
Unlike other nootropics which often modulate neurotransmitters, Lion’s Mane goes to the root of the problem. It prevents and treats nerve damage by boosting Brain Nerve Growth Factor, or neurogenesis.

Lion’s Mane can help improve focus and attention, boost thinking, repair brain cells, help depression and anxiety, and manage other neurological problems like Alzheimer’s, dementia, Parkinson’s and muscular dystrophy.
Lithium OrotateNootropicLithium retains a grim and undeserved reputation. Because it has been associated with treating serious mental issues like bipolar disorder and mania.

It turns out that the psychotic medication lithium isn’t even a drug. It’s actually an essential trace mineral required to maintain optimal cognitive function.

Studies from around the world have demonstrated the critical health benefits of lithium. One study using data from 27 Texas counties from 1978 – 1987 found that rates of suicide, homicide and rape were significantly higher in counties whose drinking water contained little or no lithium.

As a nootropic, micro-dosing with Lithium Orotate comes with a host of benefits. Lithium calms mania and mood swings by decreasing the sensitivity of norepinephrine receptors. It upregulates brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), neurotrophin-3 (NT3) and their receptors.

And lithium stimulates the proliferation of stem cells in the brain. All boosting neurogenesis and assisting in repair from all types of brain injury.

Lithium also increases brain gray matter, increases DNA replication for neurogenesis, prevents apoptosis, increases N-acetyl-aspartate (NAA), inhibits beta-amyloid secretion and protects against damage once it’s formed, chelates aluminum, and protects against glutamate toxicity.
Lopuna blanca barkAyahuasca admixture
LSA/Morning Glory Seeds/OloliuquiPsychedelic
LSD
Also see page on this site
PsychedelicScheduled
MacaNootropicMaca contains significant amounts of the amino acids’ arginine, serine, histidine, aspartic acid, glutamic acid, glycine, valine, phenylalanine, tyrosine, and threonine.

Natives in the central Peruvian Andes traditionally had their children eat Maca to improve their performance in school. Likely due to Maca’s ability to boost acetylcholine and act as an antioxidant.

Maca is used as a sports supplement by strength and endurance athletes to improve trial performance. Likely due to better energy metabolism and improved antioxidant status.

As a nootropic, Maca is known for elevating mood, increasing energy and endurance, boosting learning and memory, increasing libido, and is a potent neuroprotectant.

The purest Maca comes from high in the Andes of Peru. But Maca is also popular now in China and some Maca for export comes from that country. And should be avoided.
MagnesiumNootropicDoesn’t get the respect it should as a nootropic. The lack of adequate levels of magnesium in your body can result in brain fog, anxiety and depression.

Magnesium deficiency is nearly epidemic in our society because it is sorely lacking in our food supply.[x][xi]

Plasticity of neuron synapses is affected by the presence of adequate magnesium in brain cells. It helps improve memory and cognition. And reduces anxiety, brain fog and depression.

Magnesium can also help maintain healthy blood pressure, and help prevent sudden heart attack and stroke.

Most forms of Magnesium don’t work well as a nootropic supplement because they can’t easily cross the blood-brain barrier. A new form of magnesium called Magnesium-L-threonate is recommended for nootropic use. And is a great addition to any nootropic stack.
Magnesium OxideMedicinalPart of a classic purge; taken with lemon juice to clear GUI
Magnifying GlassAccessories
Magnolia BarkNootropicHas been used in Traditional Chinese Medicine since the Qin and Han Dynasty (221 B.C. to 220 A.D) for treating anxiety, asthma, depression, gastrointestinal disorders, headache, and more.

As a nootropic, honokiol which is one of the main active compounds found in Magnolia Bark has been shown in clinical studies to be as effective for anxiety as Valium® (diazepam).

Neurohackers report that using Magnolia Bark as a sleep supplement helps them fall asleep faster and stay asleep throughout the night.
MandrakeDeliriantOne of the traditional European wiccan plants. Dark.
MapachoStimulant
MaskAccessoriesThis is where youc an get really creative. Ideally make your own.
MDAEmpathogenScheduledLong and trippy
MDMA
Also see page on this site
EmpathogenScheduledShort and sweet
MDMA Testing KitEmpathogen Modifier
Measuring SpoonAccessoriesWith all these powders a set of spoons in various milligram amounts, while not very precise, is very helpful.
Medical tapeMedicinal
Medicinal MushroomsNootropicMushrooms have been used by humans for thousands of years as food and medicine. Of 2,000 edible mushrooms, 270 species have been identified and tested as therapeutic and preventive agents that ensure and boost human health.

But of those 270 species, only 6 are considered nootropics. And provide some benefit specifically for your brain.

And those mushrooms include: Chaga, Cordyceps, Lion’s Mane, Maitake, Oyster and Reishi.

Each of these nootropic mushrooms offer a distinct benefit to your nootropic stack. Clinical studies show they increase neurotransmitter levels, repair brain cells, improve cognitive performance and longevity, and reduce anxiety and depression.

But the medicinal mushroom market is fraught with peril. And many manufacturers pass on inferior product to unsuspecting and uneducated customers.
Medicine stickAccessories
MelatoninNootropicA hormone made in your pineal gland. And it’s this hormone your body produces when its time to go to sleep.

Melatonin levels are low during the day. And peak at about 2 – 3 AM depending on your age. After that it steadily declines until morning.

When the timing is off and melatonin drops below optimal levels, you know you’re getting old(er). Or your pineal gland is not working optimally.

When the melatonin cycle is disrupted by jet-lag, aging or stress – your ability to think clearly, memory, and decision-making abilities can suffer.

Don’t take melatonin during the day or it will disrupt your natural circadian rhythm. Melatonin as a nootropic supplement taken 1 1/2 hours before bed is ideal.
MescalinePsychedelic
MethadoneOpioid Modifier
MethamphetamineStimulantOpioid
Menthol for eyesAccessories
Methylene BlueNootropicAs a nootropic, it will likely feel different than any other nootropic on this list. It’s the first synthetic drug ever developed. First used to treat malaria back in 1891.

Methylene Blue dosageMethylene Blue assists brain cell respiration by increasing intracellular oxygen. It donates electrons to the electron transport chain within mitochondria which helps create the ATP.

Methylene Blue is a potent antioxidant. It binds to superoxide created during metabolism within brain cells. Reducing it to water and stopping the oxidative cascade at its very beginning. Before it gets a chance to do damage.

And Methylene Blue inhibits monoamine oxidase (MAOI) and acetylcholinesterase activity which increases levels of catecholamines and acetylcholine. Boosting serotonin and norepinephrine levels. Affecting anxiety, depression, energy and memory.
Metro CardAccessoriesThere’s only one
Mimosa HostilisAyahuasca admixtureGives cattle in the Midwest “the wobbles”
MindfoldNeurotechSee also Ganfeld effect
MirrorAccessories
Modafinil/ModalertNootropic
Mucuna Pruriens (L-Dopa)NootropicL-Dopa (L-3,4-dihydroxyphenylalanine) is a precursor to the formation of dopamine, norepinephrine, and epinephrine in your brain. In your body, L-dopa is synthesized from the amino acid L-tyrosine.

Dopamine deficiency is directly correlated with Parkinson’s Disease.

L-dopa easily crosses the blood-brain barrier when used as a nootropic supplement. L-dopa can increase libido, testosterone, enhances memory and learning retention. It is also reported to increase human growth hormone (HGH) levels.
***
Ayurvedic herb that replenishes dopamine. Have to eat just the right amount of powder.
Generates excellent sleep even on uppers.
Every line of cocaine is like the first, and that is why this is dangerous knowledge.
Multi-tool (Leatherman)Accessories
Musher’s SecretMedicinal
N-Acetyl L-CysteineNootropicAn amino acid that regulates the amount of glutamate and dopamine in your brain. NAC is the precursor to glutathione which reduces free radicals in your brain.

N-Acetyl L-Cysteine is used as an anti-dote to Tylenol (acetaminophen) overdose and carbon monoxide poisoning.

NAC is also used to treat ADHD, Bipolar Disorder, prevent alcoholic liver damage, Alzheimer’s Disease, eliminate heavy metals, and depression.
N-Acetyl L-TyrosineNootropicA highly bio-available form of the amino acid L-Tyrosine. The brain uses L-Tyrosine to produce dopamine. And the neurotransmitter norepinephrine which affects alertness, memory, and mood.

Dopamine is involved with libido, memory, focus, goal-oriented concentration, a mood elevator and anti-depressant.

Norepinephrine helps with alertness, working memory, focus, and executive function.

L-Tyrosine supports healthy glandular function and stress response because it helps with the synthesis of thyroid hormone and epinephrine (adrenalin).

Studies have found tyrosine to be useful for cold, fatigue, prolonged work, stress, sleep deprivation, and those suffering with hypothyroidism. Particularly studies within the military.
NADHNootropicBoosts alertness, improves mental energy and elevates mood. NADH is an antioxidant coenzyme related to the B-Vitamin family.

This coenzyme is used in the formation of ATP, the energy source produced within the mitochondria of your cells. It’s most highly concentrated in the body’s heart and brain. Both power-hungry organs.

NADH seems to decline with age, and is related to cell damage and accelerated cellular aging.

NADH also helps boost the production of dopamine and norepinephrine. This allows for greater mental performance including better memory, alertness and energy.
NarcanOpioid Modifier
Needle and threadAccessories
NefiracetamNootropicBeware, back in the mid 2000s, it was rumoured to cause testicular cancer in dogs. Proceed with caution.
And it just sounds evil!
But it DOES have its adherents. Nefiracetam is one of the newer nootropics in the racetam family of cognitive enhancers. Developed in Japan, nefiracetam is used to treat learning and memory deficit diseases.

Nefiracetam is structurally similar to Aniracetam but considered much more potent. This fat-soluble nootropic easily crosses the blood-brain barrier. It works in the hippocampus area of your brain to boost memory and recall.

Nefiracetam is used clinically to treat and prevent seizures, severe depression, and has shown neuroprotective qualities.
Neti PotAcccessory
NicotineNootropicNicotine molecules attach to nicotinic acetylcholine receptors in the brain. And seem to work by regulating other receptor systems. One obvious clue to how this works – Nicotine tends to make you more alert. And has a calming effect.

The primary neurotransmitter that Nicotine boosts is dopamine. Which may be the reason why it’s so addictive. As a result, it can also help prevent some diseases.

Dozens of clinical studies have been published showing Nicotine effective in treating Parkinson’s, ADHD, Tourette’s, schizophrenia, and other neurological disorders.

Jennifer Rusted, professor of experimental psychology at Sussex University in Britain says, “nicotine is the most reliable cognitive enhancer that we currently have”.[xv]

Turns out the addictive quality of using tobacco isn’t entirely caused by Nicotine. But by the interplay with all the other compounds found in a cigarette.

The key to using Nicotine as a nootropic is NOT by smoking a cigarette. Use a Nicotine patch or lozenge instead. If you get the right type they will fit in a Pez dispenser
Nitrous OxideDissociative
NoopeptNootropicA peptide-derived nootropic related to the racetam family. Much more potent than Piracetam (up to 1000X), its mechanism of action in your brain is similar to other racetams.

Noopept seems to stimulate dopamine, nicotinic and serotonin receptors. It boosts cognition, memory, retention, logical thinking, improves reflexes, and improves mood. Noopept has also been shown to increase Brain Nerve Growth Factor.
NutmegSpice
Oat StrawNootropicOat Straw (avena sativa) comes from green oat grass. You may have heard the term “sowing your wild oats”. Oat Straw increases luteinizing hormone in your body and is the basis for that saying. Luteinizing hormone stimulates testosterone production.

Oat Straw is an MAO-B inhibitor and increases dopamine levels in the brain. As a nootropic, Oat Straw can improve attention, cognition, concentration and focus. All benefits experienced when your dopamine and testosterone levels are optimized.
OffInsect Repellent
OpiumDepressantScheduled
OxiracetamNootropicFrom the racetam family of nootropics. And up to 5-times more potent than Piracetam. Oxiracetam stimulates acetylcholine use in the brain by working with the AMPA and NDMA receptors.

Oxiracetam can boost focus, memory, mental energy, recall, and improves fluidity of thinking. It’s most often stacked with a choline supplement because it boosts the use of acetylcholine in your brain.
Panty Hose (For filtration)Accessories
Passion flowerAyahuasca admixturea perennial vining plant native to Central and South America. Passionflower modulates GABA in your brain by inhibiting GABA uptake in synapses without affecting GABA release or GABA transaminase activity.

Passionflower is used primarily as a nootropic for reducing anxiety and promoting healthy sleep.

Passionflower is also used for reducing the symptoms of opiate withdrawal, nerve pain, convulsions, ADHD, heart palpitations, cardiac rhythm problems, high blood pressure, sexual dysfunction, and to reduce hot flashes and night sweats associated with menopause.

New studies are emerging investigating the use of Passionflower for reducing panic attacks, seizures, headache, menstrual pain, and Parkinson’s Disease.
PCPDissociativeScheduled
Perfume/CologneAccessories
PeyotePsychedelicScheduled
Pez Candy in DispenderAccessories
PhenibutNootropicDeveloped in the Soviet Union in the 1960’s. Phenibut is a GABA agonist and primarily binds to the GABAb receptor. GABAa receptor agonists include alcohol and benzodiazepines.

Phenibut can have a sedative effect and has strong anti-anxiety qualities. It can be used to combat depression, improve mood, cognitive function and motivation.
PhenylalanineNootropicAn amino acid that easily crosses the blood-brain barrier. It is not produced by the body so must be obtained by food or in supplement form. Examples of natural sources of Phenylalanine are meat and milk products.

Phenylalanine is a precursor, or assists in producing the amino acid tyrosine in your brain. Tyrosine then helps in the formation and utilization of the neurotransmitters dopamine, epinephrine, norepinephrine and melatonin.

Using Phenylalanine as a nootropic helps fight chronic pain, improves mood and boosts energy. It also helps in relief from anxiety, improves focus and boosts motivation. DL-Phenylalanine is used to help combat ADHD and Parkinson’s.
Do not take with antidepressants.
Phenylethylamine (PEA)NootropicA trace amino acid synthesized from Phenylalanine in your brain.

PEA is an endogenous (natural) amphetamine in your brain. And its structure is the basis for dozens of amphetamine-based drugs including Adderall (amphetamine), appetite suppressants, decongestants, antidepressants, and psychedelics like MDMA and mescaline.

PEA activates TAAR1 and TAAR2 receptors which in turn prevent the uptake and boosts the release of the ‘feel-good’ neurotransmitters serotonin and dopamine.

PEA has a very short half-life including as a nootropic because it’s quickly degraded by monoamine oxidase-B. So many neurohackers stack PEA with a MAO-B inhibitor like low-dose selegiline (L-deprenyl), hordenine, or Oat Straw.
PhenylpiracetamNootropicPhenylpiracetam (Carphedon) is a Russian derivative of Piracetam.[xvi] And estimated to be 30 – 60 times more potent than Piracetam. It was created by adding an extra molecule from the Phenyl group.

Easily crossing the blood-brain barrier, Phenylpiracetam is a fast-acting nootropic. It helps improve memory, recall, learning capacity, concentration, motivation and mental energy. And provides a stimulant effect.

Phenylpiracetam also helps reduce motion sickness, boosts physical performance, is anti-anxiety, and improves tolerance to cold.
Phosphatidylserine (PS)NootropicVital for the brain because this phospholipid is found in all cells, but most highly concentrated in brain cell wall membranes.

Phosphatidylserine helps in the storage, release and activity of neurotransmitters and their receptors.

Phosphatidylserine production declines as we age. And the reason why supplementation of this nootropic is so critical.

Study after study shows supplementation of Phosphatidylserine can boost cognition, focus, memory, and recall.[xix]

Phosphatidylserine (PS) is now derived from plant sources, such as soybean lecithin, or sunflower lecithin. Plant derived PS is equally effective and safer than that derived from animal brain sources.
Phosphatidylcholine (PC)NootropicA phospholipid with the highest concentration found in the brain and liver. Used as a nootropic supplement, Phosphatidylcholine (PC) helps build and repair cell membranes.

When Phosphatidylcholine is used as a nootropic, it separates into choline and sphingomyelin in your brain. Choline is needed for the synthesis of the neurotransmitter acetylcholine. And sphingomyelin helps in the development and protection of brain nerve cells.

When blood levels of choline are low, Phosphatidylcholine is cannibalized from cell walls to make acetylcholine. This eventually leads to nasty diseases like Alzheimer’s, poor memory and recall, loss of focus and brain fog, and more.
PicamilonNootropicA combination of niacin (Vitamin B3) and GABA. It was developed in the Soviet Union as an enhanced form of GABA that is capable of crossing the blood-brain barrier.

Once in your system, Picamilon separates into niacin and GABA. And produces a calming and blood vessel dilation effect.

Similar to Phenibut, Picamilon improves memory, concentration, motivation, focus, has strong anti-anxiety properties, and can lower blood pressure.

Start with the lowest possible dosage of Picamilon and see how you tolerate it. 50 – 300 mg per day is typical. Most nootropic users find somewhere between 50 – 100 mg 2 or 3 times per day is optimal.
Pine Bark Extract (Pycnogenol®)NootropicA standardized extract of French maritime pine bark. Pycnogenol® is a patented water-soluble pine bark extract containing 65-75% proanthocyanidins.

Pine Bark extract helps boost cerebral blood flow by increasing nitric oxide which helps dilate blood vessels. And helps repair and maintain the health of blood vessel linings.

Pine Bark extract is one of the most potent antioxidants discovered. Scavenging free radicals to protect neurons and other brain cells from oxidative damage.

Proanthocyanidins are condensed tannins responsible for the astringent character (pucker factor) of fruits, berries, beans, and tea. Pine Bark is higher in these bioflavonoids than most other plant sources.

Pine Bark extract is a potent anti-inflammatory, and antioxidant. And it’s not just great for your brain. It’s also great for skin health, DNA, lowering blood sugar levels, improving eye health, helps correct erectile dysfunction, calms PMS symptoms, tames asthma and hay fever, and symptoms of ADHD.
PipeAccessories
PiperineNootropicBlack pepper extract. And is used with other supplements for greater and faster absorption.

Piperine taken with a supplement like curcumin will prevent the liver from breaking down the curcumin before absorption. Piperine also elevates other supplement levels in your body which can be good in some cases. And detrimental in others.

You’ll often see BioPerine® added as a compound in some nootropic or supplement stacks. BioPerine® is a patented form of Piperine that is said to significantly enhance the bioavailability of various nutrients through increased absorption.
PiracetamNootropicPart of my Upshift recipe. Take every day for a month and you will express a profound mental boost for about 6 weeks.
developed by Romanian chemist, and the godfather of nootropics, Dr. Corneliu E. Giurgea in 1964. This is the first racetam ever developed.

Piracetam is a cyclic derivative of GABA but does not affect the GABA receptors in your brain.

Instead, Piracetam seems to influence the AMPA and NMDA receptors. This affects learning and memory processes in the brain.

Piracetam also affects the neurotransmitter acetylcholine by boosting ACh receptors into accepting or being more sensitive to acetylcholine.

As a nootropic, Piracetam boosts focus, learning, and memory. Piracetam also acts as a neuroprotectant.
Portable stereoAccessories
Potpourri Essential Oil
PQQNootropicAn enzyme cofactor, and the only nutrient known to facilitate the growth of new mitochondria in your brain cells.

Researchers found PQQ supplementation can boost the production and release of nerve growth factors in cells that support creation of new neurons in the brain. And promotes neuroplasticity that helps neurons develop the connections needed for learning and developing memories.[xx]

More studies support PQQ’s ability to increase mitochondrial density, reduce inflammation and oxidative stress, and improve learning and memory. As an antioxidant, PQQ is thousands of times more potent than Vitamin C.

Without PQQ, mitochondria wear out and brain cells age faster. Supplementing with PQQ should give you a brain energy boost. And provide anti-aging benefits.
PramiracetamNootropicA GABA-like derivative of Piracetam. It’s said to be 5 – 30 times more potent than piracetam.

Pramiracetam is a fat-soluble nootropic and highly bioavailable. It is thought to increase acetylcholine receptors in the brain. This racetam improves memory and verbal recall.[xxi]

Because Pramiracetam stimulates choline uptake in the brain it should be stacked with a good choline source like Alpha GPC or CDP Choline. And it’s fat-soluble so needs to be taken with food or a good fat source like unrefined coconut oil or MCT Oil.

Optimal dosage of Pramiracetam as a nootropic is 1,200 mg divided into 2 or 3 doses during the day.
PrismAccessories
Protein barsFood
PsilocybinPsychedelicScheduled
PterostilbeneNootropicFound in cranberries, blueberries and grapes. And is a compound similar to Resveratrol.

Pterostilbene is a very potent antioxidant, stimulates Brain-Derived Neurotrophic Factor, promotes neuroplasticity, is anti-anxiety, boosts dopamine, and helps cognition, learning and memory.

Pterostilbene works by modifying enzymes linked to glucose levels. It helps reduce blood sugar and cholesterol. Which reduces oxidative stress and prevents heart attacks and stroke.

Pterostilbene is believed to be stronger than Resveratrol and has better bio-availability. Both compounds work in different ways in a human cell so are often stacked together.
Punga amarilla barkAyahuasca admixture
QueludeDepressantScheduled, Extremely rare
QuercetinNootropicFlavanol from the flavonoid group of polyphenols found in many plants.

Quercetin boosts mitochondrial function and decreases reactive oxygen species (ROS) production which improves learning and memory.

Quercetin is a potent antioxidant and shown to inhibit Aβ aggregation, and tau phosphorylation associated with Alzheimer’s Disease. And inhibits acetylcholinesterase which in turn increases acetylcholine levels. For further therapeutic potential in treating the symptoms of Alzheimer’s.

Neurohackers use Quercetin to reduce allergy symptoms and to fight viral infections. And used as a workout supplement, Quercetin helps reduce muscle soreness.

Quercetin has the unique ability to increase claudin-4 which seals Tight Junctions and healing a leaky gut or leaky blood-brain barrier.

And recent research and user feedback shows that Quercetin may reduce symptoms of COVID-19. And has a significant capability to interfere with the replication of the virus.
RattleAccessories
Razor BladeAccessories
Remo caspi barkAyahuasca admixture
ResveratrolNootropicA polyphenol antioxidant found in the skin of grapes, Resveratrol’s purpose is to protect the grape from microbial attacks, cold weather and UV radiation.

Studies have shown Resveratrol can also boost learning, memory and cognitive power in the hippocampus section of your brain. Resveratrol can also improve blood flow and boost brain health.[xxii]

Researchers also discovered Resveratrol improves cell survival and neurogenesis in the hippocampus, boosting memory and learning
Rhodiola RoseaNootropicAMPK (adenosine monophosphate-activated protein kinase) is an enzyme found inside each of our cells and works as the body’s master regulating switch. AMPK is reduced as we age. But it is possible to increase AMPK using compounds such as Rhodiola Rosea.

When AMPK is “switched on” it triggers the use of stored energy from fats, removes fats and sugars from the blood, boosts mitochondria production, reduces inflammation, and takes out the cellular “garbage”.[xviii]

When AMPK is activated in brain cells it prevents diseases such as Alzheimer’s and Parkinson’s.
Rhodiola Rosea is a plant that grows at high altitudes and in cold regions of the world. It decreases depression and stress-related mood swings, reduces fatigue, stimulates energy and alertness, and boosts cognition.
Rohypnol”Roofy”DepressantScheduled
Rolling MachineAccessories
Rolling papersAccessories
Rose WaterAroma
RosemaryEssential Oil
Nootropic
An evergreen herb belonging to the mint family Lamiaceae. And is used world-wide as a culinary spice and medicine.

Rosemary has traditionally been used for high blood pressure, headaches, insomnia, and respiratory system-related diseases.

Rosemary is considered a powerful cardiac stimulant, a strong antiseptic, antispasmodic, calms the nerves, for arthritis, dandruff, skin diseases, and stimulates hair growth.

Compounds found in Rosemary including diterpenes, carnosic acid, and carnosol have been shown in recent studies to inhibit acetylcholinesterase (AChE) activity, is a heavy metal chelator, and protects against Amyloid-β aggregation and tau tangles. All promising therapies for Alzheimer’s Disease.

Simply smelling the aroma of Rosemary essential oil as a nootropic helps decrease alpha brain waves and increases beta brain waves. Boosting alertness and cognitive performance.
RosemaryEssential Oil, NootropicClarity
Rubber bandAccessories
Rubbing AlcoholMedicinal
Safety pinAccessories
SaffronNootropicThe dried stigma of the Crocus sativus plant native to the Middle East. And is the world’s most expensive culinary spice largely due to the way it must be grown and harvested (by hand).

Saffron has been used for thousands of years as an anxiolytic, sedative, and antidepressant.

As a nootropic, Saffron is now used for depression, PMS symptoms, post-partum depression, memory, appetite suppression, energy & stamina in athletes, and preventing neurodegenerative diseases like Parkinson’s and Alzheimer’s.

Recent studies show Saffron as effective as some popular prescription antidepressants. And can even help alleviate the sexual dysfunction caused by these drugs.

Saffron extracts (crocin & safranal) inhibit the uptake of dopamine and norepinephrine in the brain which helps improve mood.

Saffron inhibits the deposit of amyloid-β which is associated with the progression of Alzheimer’s disease. Saffron also inhibits the breakdown of acetylcholine (acetylcholinesterase) just like the current medication (donepezil) approved to treat Alzheimer’s.

Crocin and safranal which are unique carotenoids in Saffron make it a potent antioxidant. Scavenging free radicals which reduces inflammation, preventing apoptosis, and protecting brain cells and mitochondria.
SageEssential Oil
Salt & PepperFood
Salvia DivinorumPsychedelic
SAM-eNootropicA naturally occurring compound in your body. It is the amino acid methionine bound to an ATP molecule.

SAM-e helps the process of cell division and repair, and the generation of the neurotransmitters dopamine, serotonin, norepinephrine and melatonin. Which is why it’s considered a potent nootropic.

SAM-e is used to boost mood, relieve depression, improve energy levels, and reduce symptoms of fibromyalgia.
San PedroPsychedelic
SandalwoodEssential Oil
Sassafras OilIngredientPrecursor to MDMA
Scrying mirrorAccessories
Shadow PuppShadow PuppetsetsAccessoriesPut on a little show
Shiwawaku barkAyahuasca admixture
Slippery Elm throat lozengesMedicinal
Smelling SaltsMedicinal
Smudging wandAccessories
Snakebite KitMedicinal
Soap (Dr. Bronner’s HemSoap (Dr. Bronner’s Hemp Soap)p Soap)Accessories
Spoon (metal)Accessories
St John’s wortNootropicSt John’s wort (hypericum perforatum) is a plant that has been traditionally used for mood disorders and wound healing. Today its used mostly as a treatment for anxiety, depression and stress.

St John’s wort easily crosses the blood-brain barrier. And seems to work by preventing the re-uptake of serotonin in the brain.

A word of caution, however. St John’s wort is a strong CYP3A4 liver enzyme inducer. This enzyme is responsible for metabolizing psychoactive compounds in the liver. And translates to nullifying the effect of any other nootropics you may be taking.
StrawAccessories
SulbutiamineNootropicSynthesized from Vitamin B1 (thiamine). It was first developed in Japan to treat beriberi – a Vitamin B1 deficiency.

Superior to thiamine as a nootropic because Sulbutiamine easily crosses the blood-brain barrier.

As a nootropic, Sulbutiamine is taken to boost mood, memory and motivation.
SulforaphaneNootropicAn organic sulfur phytochemical found in cruciferous vegetables. But it’s most plentiful in broccoli.

Sulforaphane is needed to ensure your body gets enough sulfur. A mineral critical for the synthesis of cysteine and methionine which are needed to produce your master antioxidant Glutathione.

As a nootropic, Sulforaphane is an antioxidant, anti-inflammatory, antimicrobial, anticancer, anti-aging, neuroprotective, and antidiabetic.

It helps prevent potential damage that can be caused by the β-Amyloid aggregation associated with Alzheimer’s and Parkinson’s. Sulforaphane provides powerful defense against oxidative stress and neuronal damage caused by traumatic brain injury (TBI).

Studies show and practical user experience have proven Sulforaphane helps improve social interaction, abnormal behavior, and verbal communication in those with autism.
Sun BlockMedicinal
SunglassesAccessories
Syrian RueAyahuasca admixtureMay be more available than Banisteriopsis caapiMAO inhibitor
TaurineNootropicOne of the most abundant amino acids in your brain and body. And a featured ingredient in many popular energy drinks.

As a nootropic, taurine functions as a neurotransmitter and neuromodulator. It activates GABA and glycine receptors which affects your mood and prevents seizures.

Taurine is a neuroprotectant because it reduces intracellular free calcium, protects from mitochondrial dysfunction, modulates energy metabolism within cells, modulates longevity genes, inhibits cellular stress associated with Alzheimer’s, acts as a brain cell health “quality control” and protects against stroke.

And Taurine increases stem cells and progenitor cells in your brain which increases brain cell survival and neurogenesis.

Popular energy drinks such as Red Bull and Monster are not the best sources of Taurine for the serious neurohacker. You can get the same effect without the negatives by stacking taurine with a good caffeine source and a B-Complex supplement.
a href=”https://en.wikipedia.org/wiki/Melaleuca”>Tea TreeEssential Oil
L-TheanineNootropicInduces your brain to alpha waves 8-12 htz. relaxed.
The taste is Umami – the 5th taste. Hearty, like MSG.
Theanine naturally occurs in green tea and oolong tea, is an amino acid. L-Theanine is used as a nootropic for anxiety, learning, mood, and focus.

Since it easily crosses the blood-brain barrier, L-Theanine works quickly to increase dopamine and serotonin. The “feel good” chemicals in your brain.

Experienced nootropic users often “stack” L-Theanine with caffeine for a synergistic effect to promote cognition, motivation and attention. As a bonus, the caffeine jitters are reduced when combined with L-Theanine.
ThermometerMedicinal
ThorazineDepressantScheduledIn case of emergency break glass
TissuesAccessories
TobaccoStimulant
Trash Bag (also for purging)Accessories
TryptophanNootropicAn essential amino acid and precursor to serotonin, melatonin and niacin (Vitamin B3) in your body.

Serotonin, the “happiness molecule” relies on an adequate supply of Tryptophan for synthesis. Low levels of serotonin in the brain are often due to an inadequate supply of Tryptophan.

Tryptophan is found in abundance in oats, bananas, dried prunes, milk, tuna, cheese, bread, chicken, turkey, peanuts, and chocolate. But our bodies often have problems converting this Tryptophan to serotonin in our brain.
TurmericNootropicThe anti-Alzheimer’s spice. Turmeric is one of the main spices in curries. In parts of India where curries are eaten most often, Alzheimer’s disease is extremely rare.

Turmeric is unique in the ability to reduce inflammation common to Parkinson’s, Alzheimer’s and brain tumors.

Researchers at the Department of Neurosurgery, University of South Florida College of Medicine in Tampa, FL found that the curcuminoids in turmeric help break apart the plaque that clogs the brains in Alzheimer’s patients. [xxiv]

Turmeric has a combination of curcuminoids, volatile oils and proteins that make it anti-bacterial, anti-cancer, anti-inflammatory, and antiseptic.

Some neurohackers maintain that Turmeric or Curcumin is the best nootropic. You can increase the bioavailability of Turmeric by combining it with Piperine (black pepper extract) and a healthy fat like olive or coconut oil.
TurpentineAccessories
TweezersAccessories
TylenolMedicinal
TyrosineNootropicAn amino acid produced by Phenylalanine in your body. L-Tyrosine is directly involved in creating dopamine, norepinephrine, and epinephrine in your brain and body.

L-Tyrosine is also a precursor to thyroxine (your body’s main thyroid hormone).

You get Tyrosine from almonds, bananas, dairy products, eggs, lima beans, oats, poultry and wheat germ. Tyrosine hitchhikes on the back of amino acids like tryptophan to cross the blood-brain barrier to enter your brain.

N-Acetyl-L-Tyrosine (NALT) is a more bioavailable form of Tyrosine when used as a nootropic.

Neurohackers report that L-Tyrosine and especially NALT improves motivation and focus as well as amphetamines like Adderall if your dealing with ADHD.

L-Tyrosine also plays a role in controlling organs responsible for creating and regulating hormones in your body. Including your adrenal glands, pituitary gland and thyroid.

L-Tyrosine can sharpen memory, is anti-anxiety, boosts mood, and protects brain nerve cells from neurotoxins.
Uchu sanangiAyahuasca admixture
Uridine MonophosphateNootropicA precursor to Ribonucleic Acid (RNA). RNA provides instructions to your DNA to help create memory by facilitating connections between brain neurons (synapses).[xxv]

RNA levels decrease as we age. Supplementing with Uridine as a nootropic is one of the ultimate anti-aging tools to improve memory function.

The monophosphate portion of Uridine is the transporter that helps uridine move through your digestive tract unharmed. And delivers uridine across the blood-brain barrier.

Uridine affects the synthesis of phosphatides in the brain which are critical to cellular membranes. When you increase the synaptic proteins in your brain, you boost the number of synapses. Improving various aspects of cognition.

Uridine comes from eating broccoli, sugarcane, yeast, liver, and tomatoes.

Uridine supplementation as a nootropic uplifts and stabilizes mood, is anti-stress, helps Obsessive Compulsive Disorder (OCD), is anti-anxiety and helps modulate and normalize dopamine release.
ValerianNootropicNative to Europe and Northern Asia and has been used for millennia for headaches, anxiety, heart palpitations, high blood pressure, irritable bowel, menstrual cramps, epilepsy, and childhood behavior problems.

As a nootropic, Valerian is used primarily to lower stress and promote a good night’s sleep.

Valerian helps eliminate stress by boosting GABA, serotonin, activating adenosine receptors, and reducing the stress hormone cortisol.

Valerian promotes sleep by boosting GABA and activating adenosine receptors. Helping you to relax and get to sleep faster. You sleep better and wake up feeling refreshed with no hangover.
ValiumDepressantScheduled
Vape penAccessories
VasopressinNootropicClassic Mondo 2000 smart drug
ViagraAphrodisiac
VialsAccessories
Vick’s Vapo RubMedicinalThis is purely for MDMA rave favor
Video projectorAccessories
VinpocetineNootropicEnhances brain blood flow by dilating blood vessels. And reducing blood viscosity or thickness.

Vinpocetine is derived from the periwinkle plant. It easily crosses the blood-brain barrier. And helps improve brain blood supply, boosts oxygen and glucose use by the brain, maintains healthy levels of neurotransmitters, and promotes better concentration, focus, and memory.
VisineMedicinal
(Vitamin B1 (Thiamine)NootropicA required cofactor to produce cellular energy (ATP) from the foods you eat. It’s also needed for the synthesis of DNA and RNA.

Vitamin B1 is found in lentils, whole grains, pork, red meat, yeast, nuts, sunflower seeds, peas, milk, cauliflower and spinach.

Vitamin B1 is water soluble and is stored in your body for only 14 days. If you don’t get enough B1 you’ll experience irritability, confusion and memory problems. A severe deficiency can manifest itself as beriberi, pain, heart problems, or even paralysis.
Vitamin B3 (Niacin)NootropicBlunts the effects of LSD. Makes you itch a lot.
Used in the synthesis of Coenzyme A which helps to form Acetyl-CoA. Acetyl-CoA joins with choline to form acetylcholine.

Vitamin B3 also supports over 200 other chemical reactions in your body including cellular energy production and fatty acid synthesis.

Food sources of Vitamin B3 include beef, poultry, fish, peanuts and lentils.

Vitamin B3 (Niacin) is the only B vitamin that can be synthesized in the liver from the amino acid Tryptophan.

Niacin causes blood vessels to dilate or open up which is especially noticeable near the skin. Taking regular niacin as a nootropic supplement can cause a tingling sensation or red flushing of the sk
Vitamin B5 (Pantothenic Acid)Vitamin B5 (Pantothenic Acid)Nootropicou need Vitamin B5 (Pantothenic Acid) to synthesize coenzyme-A for the production of the neurotransmitter acetylcholine.

Your body cannot make Vitamin B5 on it’s own, so it needs to come from food or a supplement. Vitamin B5 is found in nearly every food type. But much of the Vitamin B5 in Western processed food has been removed during processing.

You may not realize the full benefit of a nootropic stack containing Alpha GPC, CDP-Choline, Acetyl-L-Carnitine or any of the racetams (that boost choline in the brain) without adding Vitamin B5.

Vitamin B5 also helps support fatty acid synthesis and cellular energy production in your body.

Using Vitamin B5 as a nootropic can boost focus, memory, learning, and reduce brain fog.
Vitamin B6 (Pyridoxine)NootropicVitamin B6 helps control homocysteine in your blood. Homocysteine is the amino acid associated with heart disease. Your body also requires Vitamin B6 to absorb Vitamin B12 and to make red blood cells and cells for your immune system.

Symptoms of low Vitamin B6 are associated with irritability, depression, nervousness, difficulty concentrating and memory loss.

Dietary sources of Vitamin B6 include poultry, tuna, salmon, shrimp, dairy products, lentils, beans, spinach, carrots, bananas, brown rice, and sunflower seeds.
Vitamin B8 (Inositol)NootropicAs a nootropic can boost serotonin levels which results in feelings of calm, heightened mental energy, and easy thought flow.

But it turns out Vitamin B8 is not a true “vitamin” because your body can produce small quantities of this compound on its own.

Vitamin B8 supports messenger signals throughout the body, including all the messenger signals between neurons in your brain.

Vitamin B8 (Inositol) is also used to control the symptoms of Obsessive Compulsive Disorder (OCD) and panic attacks.

Best food sources of Inositol are citrus fruits, green leaf vegetables, liver, brown rice, and cereals.
Vitamin B9 (Folate)NootropicAs a nootropic helps your brain make dopamine, epinephrine, norepinephrine and serotonin.

As a coenzyme, Folate participates in one-carbon transfers in the synthesis of DNA and RNA. And converts homocysteine to methionine which is used in the synthesis of S-Adenosyl-methionine (SAMe).

Folate is involved in gene expression, amino acid synthesis, and myelin synthesis and repair.

Green leafy vegetables, or ‘foliage’ are rich sources of folate. And how ‘folate’ got its name. You can also get folate from citrus fruit juice, legumes, fortified foods (more on this controversy in the extended article), and liver.

Many neurohackers, including doctors and other health professionals confuse folate with folic acid. They are NOT the same.

In the extended article, we explore the differences between folate and folic acid. And how Vitamin B9 (Folate) is critical for the fully optimized brain.
Vitamin B12 (Cobalamin)NootropicVitamin B12 (Cobalamin) deficiency is common among Western adults.[xxvi] Vitamin B12 plays a key role in the efficient conversion of carbohydrates to glucose – your cell’s source of fuel. It also helps your body to convert fatty acids into energy.

Brain fog and poor memory are two key warning signs you’re deficient in Vitamin B12. Other warning signs include fatigue, lack of energy, muscle weakness, mood swings, depression, dementia, and Alzheimer’s.

Vitamin B12 is the largest vitamin we know of, so it’s not as easily absorbed as others. As you get older the body loses the ability to transport Vitamin B12 in the cells in your large intestine where it’s pulled into your bloodstream.

The older you get the more difficult it is for you to get ANY B12 into your body. So the older you get the more likely you’ll need to supplement with Vitamin B12.

B12 in its natural form is only available through animal food sources including seafood, beef, chicken, pork, milk, and eggs.

To get an adequate supply of Vitamin B12 as you get older is really only available through supplementation.

Even though B12 is water-soluble, it doesn’t exit your body as quickly as other water-soluble supplements. It’s stored in your liver, kidneys, and other body tissues. This means a deficiency may not show up for a number of years. But by then it may be too late and irreversible brain damage can potentially result.

The best way to dose Vitamin B12 (Cobalamin) as a nootropic is sublingually (under the tongue), or a B12 shot. The first way is much less expensive and considerably less painful.

Higher quality Vitamin B12 comes as methylcobalamin or adenosylcobalamin which are the forms of B12 naturally occurring in your body. When looking for a B12 supplement or B-Complex, choose the one that contains methylcobalamin for much better absorption and use by your body.
Vitamin C (Ascorbic Acid)Nutrient, Psychedelic Modifier
Vitamin DNootropicAs a nootropic is critical for the synthesis of GABA, glutamate and glutamine, and dopamine in your brain.

Vitamin D is involved in gene expression, regulation of neurotrophic factors, neuroplasticity, and brain development early in life. All in areas of the brain associated with depression. And the neuroplasticity needed for memory formation and retrieval.

Vitamin D protects your brain from DNA damage through prevention of telomere shortening and inhibition of telomerase activity. And prevents oxidative damage to DNA.

Vitamin D3 is the fat-soluble steroid hormone form of Vitamin D. The “sunshine vitamin” is considered essential. Your skin synthesizes Vitamin D3 from ultraviolet-B (UVB) sunlight.

As a neurohacker, you should be aware that you are likely deficient in this essential vitamin. Vitamin D deficiency (hypovitaminosis D) is an undeclared worldwide pandemic affecting nearly 50% of the population on this planet.

The preferred method for getting adequate Vitamin D is from UVB sunlight on exposed skin.

But all kinds of things can interfere with getting enough Vitamin D from sunlight. Fall and Winter in both hemispheres, cloud cover, smog, skin color, sunscreen, and too much clothing are all factors.

And most of us spend so much time indoors, to get its benefits you should take Vitamin D3 as a supplement.
Voodoo dollAccessories
Water Purification TabletsAccessories
Wild TurkeyDepressant
WondercideMedicinal
Wound CleanerMedicinal
Wyra (huaira) barkAyahuasca admixture
XanaxDepressantScheduled
YohimbeAphrodisiacAfrican herb
ZincNootropicAn essential trace element absolutely required for optimal brain health and cognition.

Zinc is required for memory formation. When more zinc is available in neurons, neurotransmitters move more efficiently and stay in play longer.

Zinc helps boost BDNF which is needed for long-term potentiation and the formation of memory. A deficiency in this mineral results in poor memory.

It is integral to the activity of at least 100 enzymes. And Zinc helps lower oxidative stress which protects brain cells and cerebral blood flow. It is part of protein synthesis needed to make neurotransmitters. And it’s involved in DNA repair, synthesis and cell division.

Zinc deficiency is common even in our Western society because we often don’t get enough from food. If you’re vegan or vegetarian, you are particularly susceptible.

Zinc levels are low in those with depression. And the lower the zinc level, the more severe the depression.

Excellent nootropic resource:
Nootropics Expert

See also:
Entheogens
The Wild West of Ayahuasca
Essential Oil Guide

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